tümör ve kanser

  • Reishi Mantarı (Ganoderma) ve Kanser

    Reishi Mantarı (Ganoderma) ve Kanser

     

    Popülerlik ve Kullanım

    Göğüs kanserinden sağ kalan 4149 kişinin yaptığı bir ankete göre, Ganoderma,% 58.8'inin kendi isteğiyle Ganodermayı kullandığını kaydetti; Pozitif olarak toplumsal refah ile ilişkiliydi ve fiziksel olarak iyi olma ile olumsuz ilişkiliydi ve her iki hesapta da oldukça zayıf ilişkiliydi. [183] En azından lökositlerde, Ganoderma Lucudium, 26 aktivitesini baskı altına alırken 603 geni yukarı regüle ettiği bulundu. [5]

    2002 yılında, Ganoderma Lucidum'un küresel üretimi 4700 ton olarak tahmin edildi; 3800 ton Çin'de üretildi. [184]

    İnsanlar rehabilite edici kanser tedavisi için bu mantardan hoşlanıyorlar. Ancak bu, sosyal itibarın veya etkinliğin nedenlerinden kaynaklanıyor.

    Sitotoksisiteye Genel Bir Bakış

    Ganoderma Lucidum'un apoptozu (hücre ölümü) oldukça geniş bir hücrede indüklediği gösterilmiştir. In vitro etkinliği şu alanlarda gösterdiği kanıtlanmıştır:

    Sıçan Lösemi hücreleri (L1210) [185]
    İnsan Lösemi HL-60 [178] [186] [187]
    Diğer insan Lösemi hücre çizgileri Blin-1, U937, K562, Nalm-6 ve RPMI8226 [188]
    Akciğer kanseri hücreleri [189] [190] PG hattı ile ilgili olarak [191] [192]
    Küçük hücre akciğer karsinoması NCI-H69 ve Çok ilaca dirençli VPA türü virüs [193]
    Fare retikülosit sarkomu L-II [194]
    Sıçan sarkomu Meth-A [185]
    Murina S180 [194] [195]
    İnsan karaciğer kanseri hücreleri (hepatoma) PLC / PRF / 5, HepG2, HepG3, Huh-7 ve SMMC7721 [196] [196] [177] [190]
    Meme kanseri hücre çizgileri MDA-MB-123, [72] MCF-7, [149] T-47D, [195] ve MT-1 [197] [198]
    Prostat hücre hattı PC-3 [199] [200]
    İnsan Serviks tümörü HeLa [190] [188]
    Mesane (düşük dereceli) hücre hattı MTC-11 [201]
    Üroepitelyal kanser hücresi HUC-PC [202]
    Kolon kanseri hücre hatları HT-29 [203] ve SW480 [204]
    En azından in vitro (canlı bir canlı değil), çeşitli Ganoderma Lucidum kanşımı, tümör hücresi ölümüne yol açabiliyor. Bu görünüşte geniş ve spesifik olmayan anti-kanser etki mekanizması bir biyoaktif molekül ile sınırlı değildir. Triterpenoidler (Ganoderik asitler ve alkoller, ayrıca Lucidenik asitler) polisakaritler (düzenli ve selenyum içerenler) ve peptidoglikanların hepsi ilişkilendirilmiştir
    Fare çalışmaları ile ilgili olarak, suda çözünür polisakarit (GL-1) enjeksiyonları, farelerde transplante sarkom 180 tümörlerinin% 95-98'ini inhibe edebilir. [205] Ve benzer sonuçlar, 50 mg / kg vücut ağırlığında enjekte edilen glikoproteinler ile% 88 inhibisyon oranlarına ve test hayvanlarının üçte birinde tam regresyona sahip olan S180 hücrelerinde bildirilmiştir. [206] Bu etkiler düşük dozda 2 mg / kg vücut ağırlığı enjekte edilerek (% 74) daha düşük potens ile (% 74) tam bir gerileme gösteren hayvanların% 30'unda ve günlük oral uygulamada% 45-63'lük inhibisyonda daha az etkiliydi ve iki hastada da görüldü Sıçanlarda oral suda çözünen Reishi ekstraktını deneyen denemeler. [3] Son olarak, farelerin diyetine% 2.5 Ganoderma Lucidum'un oral uygulanması, S180 tümör taşıyan farelerin yanı sıra meme tümörleri (MM-46) inhibisyonuyla sonuçlandı. [48]

    Prostat bakımından Reishi'yi (TBS-101 olarak da adlandırılır) içeren bitkisel bir karışım, hem kanser hücresi çizgisi hem de farelere uygulandığında PC-3 tümör büyümesini bastırmayı başardı. [200] Testosteronun indüklediği tümör büyümesindeki azalmalar ayrıca, 5 alfa redüktaz inhibitörü olarak hareket etme kabiliyetine ikincil olarak görülen Ganoderma'nın triterpenoid parçasına atfedilmiştir. [207] [145]

    Akciğer adenomu oluşumu, Ganoderma Lucidum Mycelium'un 9 haftalık ağızdan uygulanmasından sonra azaltıldı [208] ve triterpenoid fragmanın Lewis akciğer kanseri hücreleri enjekte edilen farelerde koruyucu olduğu gösterildi. [113] Temel su özütlerinin enjeksiyonu da vücudun akciğer kanserinden korunmasında etkilidir. [210]

    Ganoderma Lucidum'a özgü bir triterpenoid olan 800 mg / kg lükidenik asidin (müstehcen) yüksek oral dozunun 68 gün boyunca oral yoldan verildikten sonra sıçanlarda, hepatoma (HepG2) karaciğer tümörlerinin sayısı ve büyüklüğünün% 99'a kadar azaltılması kaydedildi. [177]

    Kolon kanserlerinde, sıcak su ekstresinin önceden yüklenmesi, sıçanlarda anormal kript odakları ve kanser öncesi lezyonların gelişimini azaltabilir [211] [212]

    Fare çalışmaları, in vitro ortamda görülen anti-kanser etkilerini taklit eder gibi görünüyor ve bunların birçoğu rehabilite edici / terapötik bir tarzda da yapılmaktadır. Tek problem, rastgele farklı Ganoderma Lucidum fragmanlarını kullanan çalışmalar olup, şaşırtıcı derecede büyük miktarda hayvan çalışmaları arasında çok az kopyalama yapılmasına neden olmuştur

    13.3. Anjiyogenez

    Kan damarlarının oluşumunun tümörlere düşürülmesinin, besin ve kan akımını apoptozu indüklemek için kesebileceği (hücre ölümü), anjiyogenezin inhibe edilmesi, kemoterapinin terapötik bir mekanizması olarak görülür.

    Ganoderma'dan polisakaridlerin (F3) varlığında, anjiyojenik büyüme faktörlerinin varlığına rağmen az miktarda angiogensis (VEGFR-3 ve CD105) görülürken, in vitro anjiyogenezin regülasyonu azaltıldı. [213] Peptidoglikan içeriği aynı zamanda polisakkaritlerin yanında anjiyojenezin inhibe edilmesine katkıda bulunabilir. [214] Angiogenezideki azalma in vivo olarak kaydedildi, ancak Genistein ilavesi ile karıştırıldı; Bir soya izoflavonu. [215] 13.4. İnsan müdahaleleri Yakın tarihli bir insani müdahale, kolorektal adenomalı kişilerin tükettiği Ganoderma suda çözünür ekstraktının (günlük 1.5 g, taze mantarın yaklaşık 14g), kontrolündeki adenomların (0.66 +/- 0.1) artışını, Ganoderma grubu (-0.42 ± 0.1). [216] Ortalama adenom büyüklüğü de Ganoderma ile azalırken, kontrol grubunda artış oldu. [216] Bir başka çalışmada 12 hafta boyunca günde 5.4 g dozun ileri kolon kanserinde anlamlı bir yan etkisinin bulunmadığına dair ön kanıtlar gösterilmektedir [110] ve bu doz ve zamanlama ileri evre kanser hastalarında anlamlı bir ters etkiyle kopyalanamamıştır. [111] Bir Ganopoly (Polysaccharides) olarak bilinen Reishi'nin bir karışımı verilen akciğer kanseri hastalarında yapılan çalışma, tedaviden sonra T hücreleri, NK hücreleri ve CD4 / CD8'de artışlar bulmuş ve daha iyi refah olan hastaların% 65'inde geri bildirilmiştir [217] Şaşırtıcı derecede azdır Kanserli insanlar üzerinde insan çalışmaları. Kolon kanseri çalışması son derece umut verici görünüyor, ancak son iki çalışma aynı protokol ve dozajı kullanıyor ancak yine de biraz farklı sonuçlara varıyor. Daha fazla çoğaltma ve deneme gerekecek

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    #reishimantarı #kırmızıreishimantarı #ganodermalucidum #kanser#reishimantarıkansertedavisi #resihimantarıfaydaları #reishimantarızararları#reishimantarıkansersonuçları

  • Reishi Mantarı Nasıl Çalışır?

    Reishi Mantarı Nasıl Çalışır?

     

    Reishi mantarları nedir? Reishi mantarları diğer hastalıklarla mücadele mantarları gibi açık havada yetişen bir mantar türüdür. Kırmızı reishi mantarı doğal olarak Çin'in, Kore'nin ve Japonya'nın bulunduğu Asya bölgelerinde bulunurlar. Yenilebilir oldukları halde (bazıları bunları acı tatma ve sert bir dokuya sahip olduklarını açıklamaktadır) bunları ek, tentür veya toz formunda bulmak çok daha olasıdır.

    Reish mantarları yerden yetişir ve bitki örtüsü, tentür, çay, toz veya ekstrakt haline gelen bağsal iplikler (miselyum denir) ile birlikte "meyvemsi bir beden" oluştururlar.

    Çoğu zaman, Geleneksel Çin Tıbbında tam yetiştirilen reishi mantarı kurutulmuş, dilimlere kesilmiş, sıcak suda kaynatılarak iyileştirilmiş bir çay / çorba yapmak üzere batırılmıştır. Günümüzde, reishi ürünlerinin üreticileri, reishi'nin yüksek basınçta birkaç kez kaynatıldığı bir işleme tekniği kullanmaktadır ve aktif terkip maddelerinin bir tentür oluşturmak üzere ekstrakte edilmesine izin vermektedir.

    Geçtiğimiz onyıllar boyunca, Japonya, Çin, ABD ve Birleşik Krallık'ta düzenlenen onlarca farklı çalışma, reishi mantarlarının, aşağıdakileri içeren sayısız hastalığa karşı koruma sağlayabileceğini gösterdi:

    İltihap
    Yorgunluk (kronik yorgunluk sendromu dahil)
    Sık enfeksiyonlar (üriner sistem, bronşit, solunum yolu enfeksiyonları, vb.)
    Karaciğer hastalığı
    Gıda alerjileri ve astım
    Sindirim sorunları, mide ülseri ve sızdıran bağırsak sendromu
    Tümör büyümesi ve kanser
    Cilt bozuklukları
    Otoimmün bozukluklar
    Diyabet
    Grip, HIV / AIDS veya hepatit dahil olmak üzere virüsler
    Kalp hastalığı, hipertansiyon, yüksek tansiyon ve yüksek Kolesterol
    Uyku bozuklukları ve uykusuzluk
    Kaygı ve depresyon
    Reishi mantarları "bağışıklık modülatörü" olarak çalıştığı için hormonal dengesinin iyileştirilmesine, vücudun enuygun haline geri döndürülmesine ve tümörlerle ve kanserli hücrelerle savaşım da dahil olmak üzere bağışıklık sisteminin etkinliğini düzenler. * Araştırmalar reishi mantarlarının normalleştirici bir madde gibi hareket ettiğini gösterir. Endokrin (hormonal), bağışıklık, kardiyovasküler, merkezi sinir sistemi ve sindirim sistemleri de dahil olmak üzere çeşitli hücresel fonksiyonları ve sistemleri düzenlemektedir.

    Reishi mantarlarını kullanmayla ilgili en iyi şeylerden biri, ilaçları toksik olmayan ve herkesin herhangi bir yan etkisi yaratmayan ilaçlarla karşılaştırıldığında çok şey yapabilecek durumda olmalarıdır. Aslında, çoğu kişi enerji seviyelerinde, zihinsel yeteneklerinde ve ruh hallerinde hızlı bir düzelme fark ederken, aynı zamanda ağrı, sızlanma, alerji, sindirim sorunları ve enfeksiyonlarda bir azalma yaşar.

    Şifalarının potansiyelinin sırrı nedir peki? Reishi mantarının içerdiği çeşitli aktif maddeler şunlardır: beta-glukanlar olarak bilinen kompleks şekerler, vücuttaki hormonların öncüsü olarak görev yapabilen bitki sterolleri, kanser hücresi gelişimiyle savaşan polisakaritler ve vücudu kapatan triterpenler denilen asidik maddeler (Alerjilere tepki).

    Son bulgular, reishi mantarlarının iltihaplanmayı düşürebileceğini ve vücudun çeşitli mutasyona uğramış hücrelerin çeşitli tiplerini çıkarmak için çalışan doğal katil hücrelerin salınmasını (veya sitotoksisite) artırabileceğini önermektedir. Bu, reishi mantarını doğal bir kanser tedavisi, önleme veya kalp rahatsızlığını giderici olarak ideal hale getirir. Reishi'nin yaptığı eylem mekanizmalarından bazıları şunlardır:

     

    Sitotoksik reseptörleri (NKG2D / NCR) aktive eder
    Hücre proliferasyonunu inhibe etme
    Vasküler endotelyal büyüme faktörünü baskılamak
    Plazma antioksidan kapasitesini arttırma
    Bağışık yanıtı geliştiren
    Aşırı testosteronu dihidrotestosterona dönüştürmek

Arthur C. Brown, "Alternatif Kanser Terapisinin Dünyasına Tam Rehber" kitabında, kanser için 6 temel doğal şifa prensibi tanımlamaktadır.

Ganoderma bitkisi kanser için belirtilen 6 iyileştirme prensibinin neredeyse tamamına uygun olduğunu bulmak oldukça

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Network Marketing Nedir?

Network Marketing 21. yüzyılın ticaret modelidir. Bu konuda internet üzerinde oldukça fazla sayıda kaynak bulabilirsiniz. Biz burada daha detaylı bilgi vermeyeceğiz. Ancak toplumumuzca yanlış anlaşılan ve önyargı oluşturan bir takım

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Ganoderma'da Triterpenler

 Bitkisel maddeler olarak da bilinen Triterpenler, Ganoderma'ya acı tadını veren aktif bileşenlerdir. Bu maddeler aynı zamanda Curcubitaceae familyası için salatalık, balkabak, koloni, kemik iliği ve yumrularnd acılığa neden

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Ganoderma Yetiştiriciliği sağlık etkinliğini nasıl etkiler?

 

Eski zamanlarda, sadece derin orman ve dağ kayalıklarında Ganoderma bulabilirdiniz. Bilimsel Ganoderma yetiştiriciliği o zamana kadar iyi bilinmiyordu. Çok nadir bulunan bir bitki olarak,

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Süperoksit Dismutaz - Ganoderma'nın anti-aging etkisinin sırrı

Süperoksit Dismutaz veya SOD, Ganoderma Lucidum bitkisinde önemli bir aktif bileşentir. 

Ganodermaya, uzun süreli tüketimle yaşlanmayı yavaşlatmak için özel bir yeteneği

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Neden Ganoderma sporu, Ganoderma büyümesi ve insanoğlu için önemlidir?

Ganoderma nasıl büyür ve yayılır? Ganoderma sporunun insana yönelik önemi nedir? 

Ganoderma Lucidum meyve gövdesinin olgunlaştığı her yaz ve sonbahar, bu mantardan duman çıkıyor

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